Oocyte Rejuvenation Program
Oocyte rejuvenation program is an innovative fertility solution that offers hope to individuals of advanced maternal age (+38) to conceive. This helps couples undergoing age-related infertility challenges achieve parenthood by restoring the quality of their oocytes or eggs for fertilization.
What Is Oocyte Rejuvenation?
Oocyte rejuvenation is an advanced reproductive method designed to improve the egg maturation and mitigate age-related decline of female eggs. Using a donor’s egg, oocyte rejuvenation can improve egg quality in women of advanced age, resulting in successful conception and healthy pregnancies. This groundbreaking approach offers a new opportunity for families to address fertility challenges related to both age and genetic conditions.
How Does Oocyte Rejuvenation Work?
Oocyte rejuvenation begins with the fertilization of a healthy donated egg with the male parent sperm. Once fertilization occurs, the pronuclei of each parent are carefully removed from both zygotes.
The pronuclei from the parents’ fertilized egg are then transferred into the donor’s fertilized egg. This will result in an embryo that contains nuclear DNA from the parents and a healthy egg from the donor. Subsequently, it will be implanted into the mother’s uterus.
Although the donor’s egg will be injected, the physical and genetic traits will still come from their biological parents with the nuclear DNA unchanged.
Live Birth Rates on Age vs. Oocyte Rejuvenation
The average birth success rates tend to decline as women age due to the natural reduction in egg quality. This decline is an inevitable physiological process all women experience approaching menopause. Understanding the general trend of age-related fertility decline makes it easier for patients to receive the appropriate counseling before conducting any treatments.
Conventional IVF success rate tend to decline as women age due to the natural reduction in egg quality.
Women over 44 years old:
2% success rate per embryo transfer
Women aged 43-44:
3% success rate per embryo transfer
Women aged 40-42:
9% success rate per embryo transfer
Women over 38-39 years old:
2% success rate per embryo transfer
Women aged 35-37:
23% success rate per embryo transfer
Data from National Summary Report
On the other hand, the oocyte rejuvenation program has a higher success rate per embryo transfer. Our team has found that IVF with Oocyte is more effective than IVF with ICSI.
Live Birth Rates with Oocyte Rejuvenation
60% - 70% success rate per embryo transfer
For women aged 35 and above, the Oocyte rejuvenation program offers significantly better success rates compared to regular IVF:
96%
Fertilization Rate
56%
Blastulation Rate
61%
Euploid Blatocyst Rate
If you have undergone ineffective traditional fertility treatments, oocyte rejuvenation can be a potentially life-saving alternative. Patients that have their oocyte rejuvenated yielded a higher grades of blastocyst. The figures below highlight the program’s effectiveness in increasing pregnancy rates, offering hope to women who face challenges with IVF methods.
- Patient A
- 44 year old
- AMH: 1.8
- 3 M II
- 3 BLASTOCYSTS (4AA, 5AA, 4AB)
- Patient B
- 46 year old
- AMH: 0.48
- 7 M II
- 3 BLASTOCYSTS (4AA, 4AA, 5AA)
- Patient C
- 42 year old
- AMH: 0.5
- 5 M II
- 3 BLASTOCYSTS (4AA, 3AA, 3BB)
Ready to Begin Your Parenthood Journey?
If you are looking for expert advice on your fertility journey, Fertility Philippines is here to ease your worries, provide you with enhanced care, and guide you in every step. Let us help you start your IVF journey as hopeful as possible. Our team of trained professionals ensures you are in the right hands.